PhD projects for the competitive government fellowships 2025

PhD projects submitted for the 2025 competitive PhD fellowships at Lyon 1 Univeristy and INSA Lyon
(Updates 29/04/2025 - all projects are online)

BioDyMIA - EA 3733 - Bioingénierie et Dynamique Microbienne aux Interfaces AlimentairesCarMeN - UMR_S 1060 - Cardiovasculaire, Métabolisme, Diabétologie et Nutrition

• Cardiometabolic risk associated with obesity: role of sphingolipids in chylomicrons (Mme CALZADA) (Mis en ligne le 16/04/2025)
• Impact of plant glycolipids on metabolic health and omega-3 bioavailability (Mme MICHALSKI) (Mis en ligne le 16/04/2025)
• Food preferences, sensory and reward domains after bariatric surgery: role of gut microbiota composition and function (Mme NAZARE) (Mis en ligne le 16/04/2025)
• Impact of aromatic amino acids in the progression of chronic kidney disease (Mme KOPPE) (Mis en ligne le 16/04/2025)
• Targering mitochondria-endoplasmic reticulum interactions in various metabolic tissues: towards an innovative therapy for type 2 diabetes (Mme RIEUSSET) (Mis en ligne le 16/04/2025)
• Nutrition and cancer: impact of the synergy between metformin and fatty acids on mitochondrial bioenergetics (M PANTHU) (Mis en ligne le 16/04/2025)
• Role of TRPV1 channels in exertional heat stroke (Mme DUCREUX) (Mis en ligne le 16/04/2025)
• Cerebral metabolic rate of oxygen by MRI: clinical translation (Mme CANET-SOULAS) (Mis en ligne le 16/04/2025)
• Use of medium-chain fatty acids or their derivatives to improve the clearance of protein-bound uremic toxins in hemodialysis (M SOULAGE) (Mis en ligne le 16/04/2025)
• Study of the survival mechansims implemented during hypothermic preservation of the heart graft before transplantation (M FERRERA) (Mis en ligne le 18/04/2025)
• Transcriptional control of mitochondria-associated ER by ERRα in hepatic insulin resistance (Mme CAUSSY) (Mis en ligne le 18/04/2025)
   

CIRI - UMR 5308 - Centre international de recherches en infectiologie

• Identification and characterization of host factors enriched at intracellular assembly sites of the Crimean-Congo hemorrhagic fever virus (M COSSET) (Mis en ligne le 16/04/2025)
• Functional validation of novel mTOR regulators in NK cells and their role in antiviral immunity and viral protein trafficking (M HASAN) (Mis en ligne le 22/04/2025)

CREATIS - UMR 5220 - Centre de Recherche en Acquisition et Traitement d'Images pour la Santé

CRNL - UMR5292 - Centre de Recherche en Neurosciences de Lyon

• Multimodal PET-MR imaging: dynamic modelling of neurotransmitter release and analysis of neurovascular coupling (M COSTES) (Mis en ligne le 16/04/2025)
• Contribution of advanced biophysical techniques to the 3D neuropathology of Alzheimer's disease (M CHAVEAU) (Mis en ligne le 16/04/2025)
• Impact of SGHI fungicides on blood brain interfaces and neuroprotection in developing rats (M ZIMMER) (Mis en ligne le 23/04/2025)

HEMOSTASE ET THROMBOSE UR4609

ICBMS - UMR 5246 - Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

• New modulators of the Hepatitis B Virus capsid assembly (M LOMBERGET) (Mis en ligne le 09/04/2025)
• Sphingosine 1-phosphate in vascular calcification associated with chronic kidney disease: involvement of extracellular vesicles (Mme BRIZUELA) (Mis en ligne le 09/04/2025)
• Enzymatic synthesis of 2,5-furandicarboxylic acid (FDCA) from xylose derivatives (M DOUMECHE) (Mis en ligne le 16/04/2025)

IGFL

IP2I - UMR 5822 - Institut de Physique des 2 Infinis de Lyon

• The stealth-bomber paradigm to explain the superiority of Hadrons (Mme RODRIGUEZ LAFRASSE) (Mis en ligne le 29/04/2025)

LabTAU - UMR 1032 - Laboratoire de thérapie et applications ultrasonores

• Quantitative MRI for the detection of prostate cancer (M ROUVIERE) (Mis en ligne le 18/04/2025)
• Spatiotemporal selectivity of focused ultrasound neurostimulation: focus on the evoked electrophysiological activity using hybrid FUS / neurominitoring systems (M N'DJIN) (Mis en ligne le 18/04/2025)
• Development of a focused ultrasound treatment for uterine leiomyomas and adenomyosis (M MELODELIMA) (Mis en ligne le 18/04/2025)
• Shear waves generated by ultrasonic cavitation: application in microelastography (Mme CORTET) (Mis en ligne le 18/04/2025)
• Integrative modelling of pain-associated inflammatory and hormonal disorders in endometriosis on an original relevant 3D model of organ-on-chip (Mme BRULPORT) (Mis en ligne le 23/04/2025)

LAGEPP - UMR 5007 - Laboratoire d'Automatique, de Génie des Procédés et de Génie Pharmaceutique

• Antiparasitic activity of oxidized cholesterol derivatives against the Leishmania parasite. Encapsulation and vectorization for targeting host cells in animal models. (Mme COSTAZ) (Mis en ligne le 18/04/2025)
• Optimization of a bioreactor-based cell culture and transduction process with real-time Raman spectrometry monitoring of lentivirus production (Mme DELTON) (Mis en ligne le 18/04/2025)
• Development of new formulations for the topical treatment of cutaneous leishmaniasis (Mme AZZOUZ MAACHE) (Mis en ligne le 18/04/2025)

LaMCoS - UMR 5259 - Laboratoire de Mécanique des Contacts et des Structures 


LBTI - UMR 5305 - Laboratoire de Biologie Tissulaire et Ingénierie thérapeutique

• Involvement of elastin in epidermal homeostasis and aging (M DREBRET) (Mis en ligne le 18/04/2025)
• Deciphering the interplay between the epigenetic modifier LSD-1 and the metabolism in the cartilage homeostasis (M LAFONT) (Mis en ligne le 18/04/2025)
• Hydrogels finctionalized with antimicrobial for articular tissue repair (M MALCOR) (Mis en ligne le 18/04/2025)
• The activity and functional impact of the hypoxia signalling pathway during sky ageing (Mme SEE) (Mis en ligne le 18/04/2025)
• Injectable hydrogels enriched with bioactive nanoparticles to improve muscle repair (M SOHIER) (Mis en ligne le 18/04/2025)
• Caracterization of a new branch of the RNA damage response pathway and its implications in tissue fibrosis development (M CHAVEROUX) (Mis en ligne le 18/04/2025)
• Immunological mechanisms of mucosal immunity after sublingual administration of vaccines (Mme MONGE) (Mis en ligne le 22/04/2025)
 

• Development of a predictive co-culture model for the assessment of a novel titanium alloy applied to dental implants (Mme ATTIK) (Mis en ligne le 15/04/2025)
• Release of plastic particles during tooth brushing: environmental and health issues (Mme GRITSCH) (Mis en ligne le 15/04/2025)

LYOS - UMR1033 - Physiopathologie, Diagnostic et Traitements des Maladies Osseuses

• Towards a better understanding of alkaline phosphatase's substrates and functions (M MAGNE) (Mis en ligne le 18/04/2025)
• Impact of systeinyl leukotriens on osteoclast function - Pathophysiology and biomarkers (M PEYRUCHAUD) (Mis en ligne le 18/04/2025)

MATEIS

MMSB - UMR 5086 - Molecular Microbiology and Structural Biochemistry

• Caractérization of the mechanisms required for cell division in the bacterium Streptococcis pneumoniae (M GRANGEASSE) (Mis en ligne le 18/04/2025)
• Structural studies of viral ribonucleoprotein complexes (Mme LECOQ) (Mis en ligne le 18/04/2025)
• In silico medeling of Gram-positive bacterial cell walls: structure and mechanical properties (M MONTICELLI) (Mis en ligne le 18/04/2025)
• Caracterization of an ABC transporter from Staphylocuccus aureus involved in toxin secretion (M ORELLE) (Mis en ligne le 18/04/2025)
• Structural study of the BSP family of effector from the bacterial pathogen Brucella (M TERRADOT) (Mis en ligne le 18/04/2025)
• Integrative structural study of human UPF1 and SARS-CoV-2 nucleoprotein complex architecture (Mme FIORINI) (Mis en ligne le 22/04/2025)

• Transcriptional control of the resolution of inflammation during normal and pathological skeletal muscle regeneration (M JUBAN) (Mis en ligne le 18/04/2025)
• The role of the CHCHD4 mitochondrial protein import pathway in metabolic plasticity and muscle stem cell fate (M MOUNIER) (Mis en ligne le 18/04/2025)
• Disease mechanisms involved in the muscular comorbidities of neurological diseases (M JACQUEMOND) (Mis en ligne le 22/04/2025)
 

• Modelling adherence trajectories for patients with chronic treatment using healthcare claims databases (M CHANELIERE) (Mis en ligne le 29/04/2025)
• Health and performance of future healthcare professionals: "Feel better to heal better" (M LILOT) (Mis en ligne le 29/04/2025)

SBRI - UPR U1208 - Institut Cellule Souche et Cerveau

• UMRESTTE - UMR T9405 - Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement
  
•  Occupational noise exposure in Constances and effects on auditory and extra-auditory health - BruiSaCo (Mme CHARBOTEL) (Mis en ligne le 09/04/2025)
• LBMC - waiting to be attached to EDISS
• Bioinformatics study og bacterial effectors (Mme MARTIN) (Mis en ligne le 29/04/2025)